hrp0094p2-336 | Multisystem endocrine disorders | ESPE2021

Endocrine and metabolic complications according to genotype in Prader-Willi syndrome

Young Yoon Ju , Dong Yoo Suk , Abdumonnanovich Mamatkulov Elbek , Nailevich Gilyazetdinov Kamil , Cheon Chong Kun ,

Objective: Prader-Willi syndrome (PWS) is a complex genetic disease associated with hypothalamic-pituitary dysfunction, severe obesity and metabolic dysfunctions. The aim of this study was to describe endocrine and metabolic profiles in PWS children and young adults.We also investigated the differences in clinical outcomes according to genotype.Methods: Data of 64 children and adults with genetically verified PWS aged mo...